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Figure 11 | BMC Neuroscience

Figure 11

From: A novel role of dendritic gap junction and mechanisms underlying its interaction with thalamocortical conductance in fast spiking inhibitory neurons

Figure 11

The value of GJ mediated conductance in real neuron may be underestimated due to dendritic coupling. A) The single cell responses in FS1 &FS0, induced by a TC stimulus applied to FS1. FS1 &FS0 were coupled via GJ (gGJ = 0.4 nS). B) Experimental conditions in B are exactly the same as A except that the dendrites were removed (see B1). Note that without dendrites (and dendritic GJs), the same TC stimulus induced responses in FS1 are more excitable, however, in the postsynaptic FS cell, the GJ coupled responses are smaller. C) Overlay of the GJ coupled responses in the postsynaptic FS cell, showing that the dendritic responses are ~7 fold larger with dendrites.

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BMC Neuroscience

ISSN: 1471-2202

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