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Figure 10 | BMC Neuroscience

Figure 10

From: A novel role of dendritic gap junction and mechanisms underlying its interaction with thalamocortical conductance in fast spiking inhibitory neurons

Figure 10

Role of EPJP in regulating TC induced spike patterns in simulated barrel circuits. A1&B1) TC (6 stimuli@30 ms interval) induced spikes in an simulated layer 4 network containing a FS pair (red trace) and a spiny stellate pair (SS, black trace). A1: EPJP = 0 nS between FS pairs. B1: EPJP = 0.3 nS between FS pairs. Note that feed-forward IPSP in spiny stellate neurons (indicated by black arrows) follows each successive spike in FS cells. A2 &B2) Raster plot of spikes induced by TC (6 stimuli @ 30 ms intervals) inputs in networks without GJ coupling (A3) and with modest GJ coupling (0.3 nS, B3). C) Spike transmission efficacy in SS cells (number of spikes/number of TC inputs (C1) and spike synchronization (C2) in barrel circuits with (filled bar, gEPJP = 0.3 nS) and without GJ coupling (open bar), ***P < 0.01; ** p < 0.01, n = 10 trials.

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BMC Neuroscience

ISSN: 1471-2202

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