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Table 1 Graded denotation of FTO expression in sites involved in reward-related consumption (regular font) vs. in those that regulate primarily energy intake (bold).

From: Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

Area

Expression

Nucleus accumbens shell

+

Nucleus accumbens core

0

Ventral tegmental area

0

Parabrachial nucleus

+

Bed nucleus of the stria terminalis

+++

Supraoptic nucleus

+++

Paraventricular nucleus

++

Dorsomedial nucleus

++

Ventromedial nucleus

+++

Arcuate nucleus

+++

Lateral hypothalamus

+

  1. Other sites: septohypothalamic nucleus, ++, lateral preoptic area, 0; suprachiasmatic nucleus, +++; locus coeruleus, ++.
  2. Expression based on the visual inspection: 0, not detectable; +, weak; ++, moderate; +++, high.