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Figure 8 | BMC Neuroscience

Figure 8

From: Chondroitin sulfate proteoglycans regulate the growth, differentiation and migration of multipotent neural precursor cells through the integrin signaling pathway

Figure 8

Ech blocked the effect of Chase ABC on the differentiation of NPCs into oligodendrocytes. (A-C) Representative immunofluorescence photomicrographs of oligodendrocytes (MBP+, green) differentiated from NPCs in the control (A), Chase ABC treated (B), and Chase ABC + Ech treated (C) groups. Hoechst 33342 (blue) was used to stain the nuclei. Scale bar: 50 μm. Boxed area in B showed mature morphology of an oligodendrocyte. (D) Quantitative data demonstrate that the Chase ABC treatment on NPCs resulted in a significant increase in the number of MBP+ oligodendrocytes. Such an effect of Chase ABC could be markedly blocked by the administration of Ech. Data were shown as mean ± SEM of four independent experiments. ** P < 0.01.

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BMC Neuroscience

ISSN: 1471-2202

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