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Table 2 Selected genes abundant in ON but not in other white matter/astrocyte/macrophage libraries.

From: Expressed sequence tag analysis of adult human optic nerve for NEIBank: Identification of cell type and tissue markers

UniGene

UniGene Description

#

Notes

121333

Myelin-associated oligodendrocyte basic protein

5*

Oligodendrocyte

631992

Dystonin

5

cytoskeleton anchor/RP25 and BCMAD locus

632717

Myosin, light chain 6

5

cellular motor protein

76224

EFEMP1

4^

Doyne honeycomb retinal dystrophy/GLC1H locus

422181

S100 calcium binding protein B

4

oligodendrocytes maturation

58414

Filamin C, gamma

3

actin cytoskeleton

117060

Extracellular matrix protein 2

3

GLC1J locus

151220

Palladin

3

cytoskeletal remodeling

369068

Dynein, cytoplasmic 1, light intermediate chain 2

3

microtubule motor/interacts with dystonin

501140

KIAA1598/Shootin

3

neuronal polarization

528087

Inositol 1,4,5-trisphosphate 3-kinase B

3

Ca2+-leak

533683

Fibroblast growth factor receptor 2

3

optic atrophy

  1. The first column shows the unigene number, the second column the gene descriptor. Third column indicates the number of specific ESTs in the first 2000 sequenced clones. The fourth column (notes) give specific information of interest about these genes * A possible 6th clone in 3'UTR is also present. ^ A 5th clone was dropped because it is chimeric.