Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress

Table 3 Currently known genes that were more highly expressed in resistant than vulnerable neurons in both the present and previous study [21]

Affymetrix_ID	Gene Symbol	Description	Fold Difference (RES/VUL)^a	t-Test P Value^b
1372953_at	Ncald	neurocalcin delta	7.90	3.79E-04
1370058_at	Nefl	neurofilament, light polypeptide	3.28	9.53E-04
1390358_at	Cacna2d3	calcium channel, voltage-dependent, alpha 2/delta 3 subunit	2.91	0.019
1368810_a_at	Mbp	myelin basic protein	2.33	0.011
1373646_at	Rab15	RAB15, member RAS onocogene family	2.17	2.22E-03
1371057_at	Gabra5	gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5	2.14	0.019
1368114_at	Fgf13	fibroblast growth factor 13	2.13	1.26E-03
1368523_at	Cadps	Ca2+-dependent secretion activator	1.86	3.31E-03
1386943_at	Pllp	plasma membrane proteolipid	1.59	0.025
1368861_a_at	Mag	myelin-associated glycoprotein	1.56	0.024
1387961_at	Opcml	opioid binding protein/cell adhesion molecule-like	1.50	4.37E-04

^a,b – Calculations based on data from this study. Since the previous study [21] was a time-course study, no corresponding data were available.

ISSN: 1471-2202