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Table 6 Hypothalamic levels of TNF-α, IL-1β, and IL-10 obtained from non-heated [-]HSP72 ([-]HSP72-N) mice, non-heated [+]HSP72 ([+]HSP72-N) mice, heated [-]HSP72 ([-]HSP72-H) mice, and heated [+]HSP72 ([+]HSP72-H) mice.

From: Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke

Treatment Groups

TNF-α (pg/g)

IL-1β (pg/g)

IL-10 (pg/g)

[-]HSP72-N

7 ± 2

5 ± 2

2 ± 1

[+]HSP72-N

6 ± 2

4 ± 2

93 ± 7

[-]HSP72-H

173 ± 21a

448 ± 47a

5 ± 3a

[+]HSP72-H

44 ± 5b

59 ± 6b

101 ± 8b

  1. Samples were measured 4 h post whole body heating for heated groups or the equivalent time period for the non-heated groups. aCompared with non-heated groups (P < 0.05); bCompared with [-]HSP72 group (P < 0.05). Data are means ± S.E.M. of 12 mice per group.
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BMC Neuroscience

ISSN: 1471-2202

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