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Table 6 Hypothalamic levels of TNF-α, IL-1β, and IL-10 obtained from non-heated [-]HSP72 ([-]HSP72-N) mice, non-heated [+]HSP72 ([+]HSP72-N) mice, heated [-]HSP72 ([-]HSP72-H) mice, and heated [+]HSP72 ([+]HSP72-H) mice.

From: Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke

Treatment Groups TNF-α (pg/g) IL-1β (pg/g) IL-10 (pg/g)
[-]HSP72-N 7 ± 2 5 ± 2 2 ± 1
[+]HSP72-N 6 ± 2 4 ± 2 93 ± 7
[-]HSP72-H 173 ± 21a 448 ± 47a 5 ± 3a
[+]HSP72-H 44 ± 5b 59 ± 6b 101 ± 8b
  1. Samples were measured 4 h post whole body heating for heated groups or the equivalent time period for the non-heated groups. aCompared with non-heated groups (P < 0.05); bCompared with [-]HSP72 group (P < 0.05). Data are means ± S.E.M. of 12 mice per group.