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Table 4 The hypothalamic concentrations of malondialdehyde, oxidative-form glutathione (GSSG), reduced-form glutathione (GSH), and GSSG/GSH ratio obtained from non-heated [-]HSP72 ([-]HSP72-N) mice, non-heated [+]HSP72 ([+]HSP72-N) mice, heated [-]HSP72 ([-]HSP72-H) mice, and heated [+]HSP72 ([+]HSP72-H) mice.

From: Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke

Treatment Groups Malondialdehyde (n mol/mg protein) GSSG
(pmol/μg prot.)
GSH
(pmol/μg prot.)
GSSG/GSH
[-]HSP72-N 4.5 ± 0.3 2.2 ± 0.2 3.9 ± 0.3 0.56 ± 0.15
[+]HSP72-N 4.6 ± 0.3 2.4 ± 0.3 3.8 ± 0.4 0.63 ± 0.22
[-]HSP72-H 9.9 ± 0.8a 3.6 ± 0.2a 2.0 ± 0.4a 1.80 ± 0.31a
[+]HSP72-H 4.8 ± 0.4b 2.5 ± 0.3b 4.2 ± 0.4b 0.59 ± 0.18b
  1. Samples were measured 4 h post whole body heating for heated groups or the equivalent time period for the non-heated groups. aCompared with non-heated groups (P < 0.05); bCompared with [-]HSP72-H group (P < 0.05). Data are means ± S.E.M. of 12 mice per group.