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Table 2 The concentrations of glutamate, glycerol, lactate/pyruvate ratio, DHBA, and nitrite in the extracellular levels of the hypothalamus obtained from non-heated [-]HSP72 ([-]HSP72-N) mice, non-heated [+]HSP72 ([+]HSP72-N) mice, heated [-]HSP72 ([-]HSP72-H) mice, and heated [+]HSP72 ([+]HSP72-H) mice.

From: Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke

Treatment Groups Glutamate (% of baseline) Lactate/pyruvate ratio Glycerol (% of baseline) Nitrite (μM) DHBA (% of baseline)
[-]HSP72-N 100 ± 3 9 ± 1 102 ± 3 14 ± 2 100 ± 5
[+]HSP72-N 100 ± 2 8 ± 2 101 ± 2 15 ± 3 101 ± 6
[-]HSP72-H 178 ± 9a 213 ± 14a 156 ± 7a 98 ± 9a 142 ± 7a
[+]HSP72-H 108 ± 6b 25 ± 4b 21 ± 3b 26 ± 4b 109 ± 6b
  1. Samples were measured 4 h post whole body heating or the equivalent time period for non-heated groups. aCompared with non-heated groups (P < 0.05); bCompared with [-]HSP72-H group (P < 0.05). Data are means ± S.E.M. of 12 mice per group.