Volume 9 Supplement 1
Self-sustaining non-repetitive activity in a large scale neuronal-level model of the hippocampal circuit
© Scorcioni et al; licensee BioMed Central Ltd. 2008
Published: 11 July 2008
The mammalian hippocampus is involved in spatial representation and memory storage and retrieval, and much research is ongoing to elucidate the cellular and system-level mechanisms underlying these cognitive tasks. Modeling may be useful to link network-level activity patterns to the relevant features of hippocampal anatomy and electrophysiology. Investigating the effects of circuit connectivity requires simulations of a number of neurons close to real scale.
Results and Discussion
This work was supported by NIH grants NS39600, AG025633 and NSF grant SGER 0747864.
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