Volume 9 Supplement 1
Functional connectivity of brain network during character imagery
© Yu and Tang; licensee BioMed Central Ltd. 2008
Published: 11 July 2008
Previous results indicate cognitive processes of brain areas usually activate during visual mental imagery , however, few studies address the functional connectivity between these active regions. In the present study, a low-frequency (0–0.15 Hz) coherence method was used to analyze the event-related fMRI data from a task in which participants visualized digits and letters (termed as character imagery). The coherence method was discussed in detail in Sun et al . A band-averaged coherence of 1 would indicate strong functional interaction between areas, and a coherence of 0 would indicate the total absence of such a relationship . The brain networks include left IFG (inferior frontal gyrus), left FUS (fusiform gyrus), left CUN (cuneus) and left SPL (superior parietal lobule). All of the four ROIs (Regions of Interest) were selected based on previous studies [1, 3]. Nine right-handed subjects participated in this study. The materials of the character imagery task were based on a subset of those used by Kosslyn et al . Statistical parametric mapping analysis was performed using SPM2 running under Matlab 6.5.
Results and conclusion
We thank Drs. Stephen M Kosslyn, William L Thompson, Giorgio Ganis at Harvard University for generously providing imaging data and insightful comments. We thank Dr. Lee M. Miller for helpful suggestions about the low-frequency coherence analysis method. This work was supported in part by National Natural Science Foundation of China Grant 30670699, Ministry of Education Grant NCET-06-0277 and 021010.
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