Volume 8 Supplement 2
Network reconstruction in the presence of unmeasured neurons
© Nykamp; licensee BioMed Central Ltd. 2007
Published: 6 July 2007
We present a method to determine whether a correlation in the spikes of two neurons is due to a causal connection between the neurons or due to common input originating from unmeasured neurons. The distinction is based on a point-process model of how a neuron's spiking probability can depend on both its own spiking history and a stimulus (or other external variables). Although the results depend on selecting a parametric model that captures essential features of the neural response, a large class of models can be used with the network analysis. Hence, the analysis could be applied to probe circuitry in a large range of neuronal systems.
This article is published under license to BioMed Central Ltd.