Volume 10 Supplement 1
Emergent phenomena in human EEG: a bifurcation theory approach
© Frascoli et al; licensee BioMed Central Ltd. 2009
Published: 13 July 2009
A recently proposed mesoscopic mean-field theory of mammalian cortex electro-rhythmogenesis describes the salient features of electrical activity in the cerebral macrocolumn, with the use of inhibitory and excitatory neuronal populations . Numerical solutions to the defining non-linear equations have revealed two interesting emergent phenomena: i) the appearance of large-scale spatial coherent 40 Hz oscillations in the model cortex, which has shown to be experimentally related to cognitive activity , and ii) a surge in spectral EEG power – when the brain is subject to general anesthetics – as a function of their concentration , a clinically established effect known as the "biphasic" response. Given that quasi-linear approximations have been unable to capture the dynamical mechanism that trigger these phenomena, a bifurcation analysis  of physiologically relevant parameter sets was performed.
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This article is published under license to BioMed Central Ltd.